Page last updated: 2024-12-09

2-{[(9H-9-fluorenylmethoxy)carbonyl]amino}benzoic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID978386
CHEMBL ID524172
CHEBI ID183678
SCHEMBL ID119223

Synonyms (44)

Synonym
OPREA1_661448
fmoc-2-abz-oh, 97%
MAYBRIDGE4_001966 ,
HMS1526J08
2-(9h-fluoren-9-ylmethoxycarbonylamino)benzoic acid
BRD-K68581587-001-01-2
CHEMBL524172
2-(9h-luoren-9-ylmethoxycarbonylamino)benzoic acid
2-{[(9h-9-fluorenylmethoxy)carbonyl]amino}benzoic acid
CHEBI:183678
AKOS009156751
FT-0679799
150256-42-1
fmoc-2-abz-oh
AB05317
SCHEMBL119223
bdbm196155
us9211296, table 6, 9
bio4a5
benzoic acid, 2-[[(9h-fluoren-9-ylmethoxy)carbonyl]amino]-
2-((((9h-fluoren-9-yl)methoxy)carbonyl)amino)benzoic acid
2-[[(9h-fluoren-9-ylmethoxy)carbonyl]amino]benzoic acid
n-fmoc-anthranilic acid
F0923
n-[(9h-fluoren-9-ylmethoxy)carbonyl]anthranilic acid
2-(fmoc-amino)benzoic acid
n-2-(9-fluorenylmethyloxycarbonyl)amino-benzoic acid
mfcd00235883
CCG-254198
fmoc-abz-oh
fmoc-anthranilic acid
2-(((9h-fluoren-9-yl)methoxy)carbonylamino)benzoic acid
2-n-fmoc-aminobenzoic acid
AS-10270
fmoc-(2)abz-oh
I10504
M06085
EN300-1718679
2-({[(9h-fluoren-9-yl)methoxy]carbonyl}amino)benzoic acid
A884184
CS-W009398
Z1136511498
SY051364
2-[[[(9h-fluoren-9-yl)methoxy]carbonyl]amino]benzoic acid
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
fluorenesAn ortho-fused polycyclic arene in which the skeleton is composed of two benzene rings ortho-fused to cyclopentane.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (13)

Assay IDTitleYearJournalArticle
AID540299A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis2010Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
AID588519A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities2011Antiviral research, Sep, Volume: 91, Issue:3
High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors.
AID1794808Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL).2014Journal of biomolecular screening, Jul, Volume: 19, Issue:6
A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum.
AID1794808Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL).
AID390732Antiviral activity against Vaccinia virus WR in BSC1 cells assessed as reduction in plaque formation after 20 hrs2008Journal of medicinal chemistry, Oct-23, Volume: 51, Issue:20
Identification of non-nucleoside DNA synthesis inhibitors of vaccinia virus by high-throughput screening.
AID390733Antiviral activity against Vaccinia virus WR in BSC1 cells assessed as protection from virus-induced lysis of cell monolayer after 20 hrs2008Journal of medicinal chemistry, Oct-23, Volume: 51, Issue:20
Identification of non-nucleoside DNA synthesis inhibitors of vaccinia virus by high-throughput screening.
AID390735Cytotoxicity against african green monkey BSC1 cells after 72 hrs WST-1 based assay2008Journal of medicinal chemistry, Oct-23, Volume: 51, Issue:20
Identification of non-nucleoside DNA synthesis inhibitors of vaccinia virus by high-throughput screening.
AID390737Selectivity index, TC50 for african green monkey BSC1 cells after 20 hrs to EC50 for Vaccinia virus WR in BSC1 cells after 20 hrs by cell protection assay2008Journal of medicinal chemistry, Oct-23, Volume: 51, Issue:20
Identification of non-nucleoside DNA synthesis inhibitors of vaccinia virus by high-throughput screening.
AID390736Cytotoxicity against african green monkey BSC1 cells after 120 hrs WST-1 based assay2008Journal of medicinal chemistry, Oct-23, Volume: 51, Issue:20
Identification of non-nucleoside DNA synthesis inhibitors of vaccinia virus by high-throughput screening.
AID390731Inhibition of Vaccinia virus DNA synthesis in by rapid plate assay2008Journal of medicinal chemistry, Oct-23, Volume: 51, Issue:20
Identification of non-nucleoside DNA synthesis inhibitors of vaccinia virus by high-throughput screening.
AID390741Antiviral activity against Vaccinia virus WR in BSC1 cells assessed as retention of antiviral potency by measuring exogenous double stranded DNA trapping2008Journal of medicinal chemistry, Oct-23, Volume: 51, Issue:20
Identification of non-nucleoside DNA synthesis inhibitors of vaccinia virus by high-throughput screening.
AID390734Cytotoxicity against african green monkey BSC1 cells after 20 hrs WST-1 based assay2008Journal of medicinal chemistry, Oct-23, Volume: 51, Issue:20
Identification of non-nucleoside DNA synthesis inhibitors of vaccinia virus by high-throughput screening.
AID1159607Screen for inhibitors of RMI FANCM (MM2) intereaction2016Journal of biomolecular screening, Jul, Volume: 21, Issue:6
A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's4 (66.67)24.3611
2020's1 (16.67)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.68

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.68 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.63 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.68)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]